Next Generation Sequencing & Big-Data Analysis
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About

Genome Life Sciences addresses this challenge by leveraging its two decades of experience in basic research in bioinformatics and computational genomics. Our team's humble beginnings are rooted in innovations in genomics. As pioneers of novel bioinformatic algorithms, we have defined a new direction in NGS data analysis and research into the genome biology of diseases.

Massively parallel sequencing of DNA is outpacing all technological advancements in physical and biological sciences. With significant reduction in the cost of DNA sequencing, the genome data generated by next generation approaches has triggered a revolution, and have brought forth many challenges for meaningful data analysis and understanding of human health and disease.

Today, we stand at the landmark where our advanced analytical methods have begun to aid researchers and clinicians across the globe. Our proprietary algorithms for genomic analysis stand as cornerstones of biomarker discovery and personalized patient diagnosis. With a talented scientific team that made this possible, our product and service platforms aim at providing the most significant and actionable biological information for basic research and clinical and agricultural applications.

Genome Life Sciences

NOVEL OMICS-ANALYTICS
SPECIALLY TAILORED FOR
CLINICAL RESEARCHERS! 

Services

Genome Life Sciences’ service offerings encompass analysis of genomes, exomes, transcriptomes and proteomes. Our end-to-end services range from data assembly and interpretation from all sequencing platforms, algorithms development for advanced research, and bioinformatics software development for custom projects.

The flexibility and resolutions we provide in routine data management and analysis with customized publication-ready reports and results will save your valuable time and cost, and enable you to seamlessly focus on your research while we take care of your analytical needs.

OUR KEY RESEARCH AREAS

Agrigenomics

  • Use of NGS to identify plant genes conferring resistance to (i) environmental conditions, (ii) effects of herbicides, (iii) pests
  • Development of Bio-fortified foods, e.g., iron-rich pearl millet, zinc-rich rice & wheat
  • Development of large-scale genomic resources to enhance selective breeding
  • Development of pharmacrops

Metagenomics & Microbial Genomics

  • Discovery of novel genes for crop improvement
  • Bioremediation of Xenobiotics by looking for pharmacologically interesting genes (e.g. antibiotics, herbicides and insecticides) that exist in organisms that cannot be cultured
  • Study plant adaptations in unfavorable environments

 

Animal Husbandry

  • Identifying genes in livestock that control growth, energy metabolism, development, appetite, reproduction and behavior, as well as other traits that have been manipulated by breeding
  • Discovering genes underlying important traits of dairy animals such as heat tolerance, disease resistance, meat quality and lactation

Clinical Genomics

  • Identify clinically actionable mutations
  • Outbreak monitoring to identify the sources and spread of infections
  • Antibiotic resistance surveillance
  • Personalized medicine
  • Emerging pathogen surveillance
  • Identify genotypes underlying diseases

GLS IS A MARKET LEADER IN
START-TO-FINISH NEXT-GENERATION SEQUENCING
AND DATA ANALYSIS SERVICES

Products

  • In order to accelerate discovery in the fields of genomic medicine and plant biotechnology, our crew scientists have been relentlessly spending transformative hours in optimizing management, analysis and mining of high-throughput molecular biology data.

    We provide a highly scalable and automated platform that enables users to comprehensively and rapidly analyze their next-generation sequencing data. Various NGS applications and sequencing platforms are supported. The workflows can be quickly customized as needed. Results are delivered as a detailed report.

    • Agricultural and veterinary studies
    • Clinical and translational research
    • Bioinformatics R & D project management

    The product suit comes with

    • Start-to-finish NGS application-specific data analysis workflows and Integration of results with our proprietary IGR (Integrated Genomics Resources) places the results in biological context
    • Analytical and visualization tools to enable scientists decode knowledge from large complex datasets

     

    Genome Life Sciences
    Key Features
    • Comprehensive NGS (WGS, WES, RNA-Seq, miRNA-Seq, Methyl-Seq, ChIP-Seq) data analysis
    • Analysis and visualization of alternative transcription, alternative splicing data and exon-intron architecture
    • Annotated, centralized disease-specific variant database
    • Comprehensive analysis with clinical relevance
    • End-to-end workflow integration
    • Completely portable genomics solution for cloud-based and local distributed cluster environments
    • Big data analytics
    Key Applications
    • Variant detection and effect prediction on sequence & structure
    • Chromosomal aberration and gene fusion analysis
    • Alternate splice sites and transcript prediction
    • Gene set analysis, Pathways and Networks of Clinical significance
    • Pathogen detection system
    • Novel Splice sites, Transcripts, Genes prediction
  • Genome Life Sciences
    Tools
    • Holistic database for comparative analysis of the exon–intron structures of protein domains in eukaryotes (Homo sapiens, Mus musculus, Bos taurus, Rattus norvegicus, Danio rerio, Gallus and Arabidopsis thaliana)
    • Specialized platform offering the largest collection of AT & AS splicing data readily available for your analysis.
    • A large splice-centric curated data collection for visualization and analysis of splicing and AS events.
    • Statistical search and analysis engine for pinpointing disease-causing variants in functional regions of genes.
    Product Highlights
    • Complex mechanisms of alternative transcription and splicing events are made easy to read and capture for biological inference
    • Analyze known and predict potential splice sites
    • Analyze functional changes and effects in proteins due to transcription and splicing
    • Molecular mechanisms of splicing induced disease states
    • Functional correlations among genes, proteins, pathways, disease and development
    • Comprehensive graphical display with simultaneous viewing of domains and gene structure details
    • Color-coded revealing display format
    • Dynamic platform to analyze cancer causing mutations

OUR CLOUD INFRASTRUCTURE PROVIDES
COMPLETE STORAGE MANAGEMENT OF RAW
AND PROCESSED SEQUENCE DATA

Contact

Contact Form

Contact Details

383, 1st Cross Street,
Nehru Nagar, OMR,
Kottivakkam, Chennai - 600096
Tamilnadu, India

Phone: +91-44-43593750, +91-44-24543750
Email: info@genomels.com